sodium bicarbonate side effects

Background and objectives: Metabolic acidosis contributes to muscle breakdown in patients with CKD, but whether its treatment improves functional outcomes is unknown. sodium bicarbonate side effects. For Boosting Athletic Performance – Supplemental dosage of sodium bicarbonate should be 200-300 mg/kg range before exercise. This toxic substance may inflame your throat or respiratory tract and may cause difficulty swallowing, hoarseness or wheezing. pregnancy, upcoming surgery, etc. Though it’s considered safe, some are convinced it has potentially dangerous health effects. What are some side effects that I need to call my doctor about right away? Along with its needed effects, a medicine may cause some unwanted effects. Check with your doctor as soon as possible if any of the following side effects occur while taking sodium bicarbonate: Frequent urge to urinate. the bicarbonate should be stopped and the patient managed according to the degree To do so may keep the other medicine from working properly. All drugs may cause side effects. nausea or vomiting. Tell your doctor if any of these symptoms are severe or do not go away: increased thirst; stomach cramps; gas; Severe side effects. Sodium bicarbonate side effects can include metabolic alkalosis, edema due to sodium overload, congestive heart failure, hyperosmolar syndrome, hypervolemic hypernatremia, and hypertension due to increased sodium. Which drugs or supplements interact with sodium bicarbonate? include febrile response, infection at the site of injection, venous thrombosis General Side Effects. Sodium bicarbonate is an antacid used to relieve heartburn and acid indigestion. Suggested Dosage. So, there are side effects. Sodium bicarbonate 500mg capsules contain approximately 6 mmol each of Na + and HCO 3-; Sodium bicarbonate 600mg capsules contain approximately 7 mmol each of Na + and HCO 3-.. © 1998-2020 Mayo Foundation for Medical Education and Research (MFMER). Sodium Bicarbonate (sodium bicarbonate 5% injection) is an electrolyte alkalinizer used to treat metabolic acidosis, which can occur in severe renal disease, uncontrolled diabetes, circulatory insufficiency due to shock, anoxia or severe dehydration, extracorporeal circulation of blood and severe primary lactic acidosis. Call your doctor for medical advice about side effects. These are not all of the side effects that may occur. More frequently reported side effects include: congenital anomalies and abdominal pain. the fluid for examination if deemed necessary. Severe alkalosis may be controlled by parenteral injections A member asked: last night me and my husband took a teaspoon of sodium carbonate by mistake thinking it was bicarbonate (sodium bicarbonate). or phlebitis extending from the site of injection, extravasation, and hypervolemia. Sodium Bicarbonate may interact with other drugs. See additional information. Stop using sodium bicarbonate and call your doctor at once if you have: severe stomach pain; swelling, rapid weight gain; or. What are the side effects of sodium bicarbonate? Advertising revenue supports our not-for-profit mission. You may report side effects to FDA at 1-800-FDA-1088. Copyright © 2020 IBM Watson Health. Sodium bicarbonate (baking soda) is a chemical compound with a variety of uses, including in oral and digestive health and possibly athletic stamina. Known side effects include: belching, flatulence , stomach pain, and edema (water retention). Turn recording back on. Baking Soda Side Effects – Sodium bicarbonate is a popular chemical compounds used in cooking. In serious cases, you could have severely low potassium levels, intestinal obstruction/necrosis, and perforation of the bowel wall. If you notice any other effects, check with your healthcare professional. Side Effects of Sodium Bicarbonate. ... Risks and Side Effects . Sodium Bicarbonate may interact with other drugs. What Is Sodium Bicarbonate E500? Sodium bicarbonate may cause side effects. Dr. Addagada Rao answered. Alternatively, 0.65-2.6 g 4 hourly. shortness of breath (even with mild exertion). Sodium bicarbonate is injected intravenously (by IV) for heart resuscitation, poor kidney function, cocaine toxicity, to prevent kidney damage caused by dyes used during some X-ray exams, poisoning from certain allergy medications, reviving newborns, pesticide poisoning, prevention of chemotherapy side effects, breakdown of muscles, and fluid build-up in the lungs caused by a certain chemical. It is a salt composed of sodium ions and bicarbonate ions. In Summary. headache (continuing) loss of appetite (continuing) mood or mental changes. Our general interest e-newsletter keeps you up to date on a wide variety of health topics. The evidence to support the use of sodium bicarbonate in skin health comes from a single clinical trial and some anecdotal evidence. Drug information provided by: IBM Micromedex. If any of these effects continue or become bothersome, inform your doctor. The hemorrhage gets triggers by rapid infusion of sodium bicarbonate. Nervous system side effects of sodium bicarbonateincludes coma, tetany, irritability, mental stupor and intraventricularhemorrhage. Side effects Mild side effects. Oral antacid: 325 mg to 2 g 1-4 times per day. If an adverse reaction does occur, discontinue the infusion, evaluate the patient, For the Consumer. What is the dosage for sodium bicarbonate? So, there are side effects. Our expert will review it and respond soon. Sodium Bicarbonate Injectable works by neutralizing stomach acid. received an overall rating of 8 out of 10 stars from 16 reviews. Side Effects of Using Baking Soda: Using sodium bicarbonate topically for the skin, hair and nails is absolutely safe and nontoxic. Tell your doctor right away if you have any serious side effects, including: swelling hands/ ankles /feet, unusual weight gain. ).Some health conditions may make you more susceptible to the side-effects of the drug. Sodium/Bicarbonate uses and side effects (34) PubMed Health. Call your doctor for medical advice about side effects. Sodium bicarbonate side effects. Sodium bicarbonate is also used to treat certain drug intoxications, including barbiturates, or salicylates or methyl alcohol poisoning. These side effects may go away during treatment as your body adjusts to the medicine. Although the following side effects occur very rarely when this medicine is taken as recommended, they may be more likely to occur if it is taken: in large doses, for a long time, or by patients with kidney disease. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. no side effects yet. Adult : PO Dyspepsia 1-5 g 4-6 hourly as necessary. Some health effects (increase in metabolic rate or attenuation of metabolic acidosis) can be achieved at more reasonable doses, such as 5-10g, and may be more practical for nonathletes. This is why MedlinePlus, the U.S. Medical Library, has a section on "Baking Soda Overdose," where it is stated that baking soda can be poisonous in large amounts. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic. Search: Sodium/Bicarbonate uses and side effects; Number of items displayed: Feed name: Recent Activity. Your doctor also may prescribe sodium bicarbonate to make your blood or urine less acidic in certain conditions. Side effects … It can also be used for reducing acid in urine and may also prevent different metabolic problems. Read the entire FDA prescribing information for Sodium Bicarbonate (Sodium Bicarbonate 5% Injection). Call your doctor or get medical help if you have any side effects that bother you or do not go away. Amongother respiratory side effects, the suppressed respiratory drive is the mostsignificant of them all. * Report new side effects to us by sending email to foodchemmis08@foodchem.cn. Notify your doctor if you develop: muscle weakness, slow reflexes and confusion, swelling of the feet or ankles, black tar-like stools, coffee-ground vomit. Benefits of sodium bicarbonate can be observed with a single dose taken 60-90 minutes before exercise, but supplementation should be approached cautiously as it can cause gastrointestinal side effects if too much is taken at once or, if its consumed too rapidly. Sodium bicarbonate may also be used for purposes not listed in this medication guide. You may report side effects to the FDA at 1-800-FDA-1088. 4. Rapidor prolonged administration of sodium bicarbonate can sometimes inducehyernatremia, hypokalemia, hypochloremia, hyperosmolarity and metabolicalkalosis. It should be taken 60 to 90 minutes before anaerobic activities for maximum benefit. For a long period of time. If you have any of the following symptoms, stop taking sodium bicarbonate and call your doctor immediately: severe headache; upset stomach Introduction and hypothesis: In this study, we planned to explore the effects of sodium bicarbonate orally (NaHCO3) treatment on female patients with lower urinary tract symptoms (LUTS) who have acidic urine pH values (<6). During pregnancy, Sodium Bicarbonate should only be used if prescribed. Side effects include: Low levels of potassium causing twitching, muscle weakness, ‘pins and needles’ in the hands or feet, irritability or abnormal heart rhythm ), allergies, pre-existing diseases, and current health conditions (e.g. Common side effects of sodium bicarbonate include:. Sodium Bicarbonate(Sodium Bicarbonate 5% Injection) side effects drug center, Medical Editor: John P. Cunha, DO, FACOEP. Like all medicines, Sodium Bicarbonate Injection can cause side effects, although not everybody gets them. of calcium gluconate or an acidifying agent such as ammonium chloride. Get emergency medical help if you have signs of an allergic reaction : hives; difficult breathing; swelling of your face, lips, tongue, or throat. Check with your doctor as soon as possible if any of the following side effects occur: Some side effects may occur that usually do not need medical attention. WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Call your doctor for medical advice about side effects. drugs a-z list Other metabolic side effects of baking soda includes hyporeninemia,hypoaldosteronemia and the expansion of intravascular volume. Sodium bicarbonate (baking soda) is a chemical compound with a variety of uses, including in oral and digestive health and possibly athletic stamina. Applies to omeprazole / sodium bicarbonate: oral capsule, oral packet. For patients on a sodium-restricted diet: This medicine contains a large amount of sodium. The effects of sodium bicarbonate on insulin sensitivity have only been studied in a few, small studies with mixed results. What are some other side effects of Sodium Bicarbonate Tablets? Reactions which may occur because of the solution or the technique of administration This is not a complete list of side effects and others may occur. Side Effects of Sodium Bicarbonate. Sodium bicarbonate is indicated in the treatment of metabolic acidosis which may occur in severe renal disease, uncontrolled diabetes, circulatory insufficiency due to shock or severe dehydration, extracorporeal circulation of blood, cardiac arrest and severe primary lactic acidosis. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Other side effects not listed may also occur in some patients. However, high doses may cause headache, nausea or irritability. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Less common. Repeat doses may be considered in the setting of prolonged cardiac arrest only after adequate alveolar ventilation has been established Common side effects of sodium_bicarbonate include: This is not a complete list of side effects and other serious side effects may occur. Baking soda, or sodium bicarbonate, is most commonly used to relieve heartburn because it’s a basic chemical that helps to neutralize acid. Sodium bicarbonate (baking soda) is generally well tolerated. Possible side effects. institute appropriate therapeutic countermeasures and save the remainder of Sodium Bicarbonate E500, known as baking soda, is a chemical leavening agent. If you notice other effects not listed above, contact your doctor or pharmacist. muscle pain or twitching. Mayo Clinic does not endorse companies or products. Should alkalosis result, Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. To do so may increase the chance of side effects. Common side effects of sodium bicarbonate include: fever; infection at the site of injection; blood clots in the veins ; fluid leakage from injection site, or; fluid overload (hypervolemia) Dosage of Sodium Bicarbonate depends on the condition being treated and the weight of the patient. Digestive Disorders: Common Misconceptions, Sodium Bicarbonate Professional Information. Baking soda, or sodium bicarbonate, is most commonly used to relieve heartburn because it’s a basic chemical that helps to neutralize acid. About how much does an adult human brain weigh? Sodium bicarbonate via oral consumption may cause a panic attack in those with a panic disorder .Digestion discomfort is also present with sodium bicarbonate use in some individuals .Those with chronic kidney disorder have a higher risk of heart failure with a higher amount of bicarbonate in their blood .Oxygen flow to the heart may also be reduced with the use of sodium bicarbonate in some patients . What are the side effects of Sodium Bicarbonate? If you notice any other effects, check with your healthcare professional. However, many people have no side effects or only have minor side effects. Sodium Bicarbonate (Sodium Bicarbonate 5% Injection). 55 years experience General Surgery. Your browsing activity is empty. MedlinePlus does not recommend athletes take baking soda as … Do not take sodium bicarbonate: Within 1 to 2 hours of taking other medicine by mouth. Sodium Bicarbonate E500 is a chemical compound with the formula NaHCO3. Find patient medical information for Sodium Bicarbonate Intravenous on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Activity recording is turned off. As Sodium Bicarbonate is widely known as safe, there is no limit on dosage of intake. This can happen on the skin as well. This is why MedlinePlus, the U.S. Medical Library, has a section on "Baking Soda Overdose," where it is stated that baking soda can be poisonous in large amounts. Aggravated congestive heart failure (CHF) Cerebral hemorrhage; Swelling (edema) High blood sodium levels; Low blood calcium levels; Low blood potassium levels Common side effects of sodium bicarbonate include: Dosage of Sodium Bicarbonate depends on the condition being treated and the weight of the patient. Clear Turn Off Turn On. of alkalosis present. All rights reserved. All rights reserved. See below for a comprehensive list of adverse effects. Doctors give trusted answers on uses, effects, side-effects, and cautions: Dr. Esguerra on sodium bicarbonate side effects: Common reactions are nausea and gastric irritation. Our Sodium Bicarbonate (sodium bicarbonate 5% injection) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. Sodium bicarbonate is available in generic form. This product appears as a […] This content does not have an English version. Applies to potassium bicarbonate: oral capsule. Vaccine updates, safe care and visitor guidelines, and trusted coronavirus information, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, Sodium Bicarbonate (Oral Route, Intravenous Route, Subcutaneous Route), FREE book offer – Mayo Clinic Health Letter. See what others have said about , including the effectiveness, ease of use and side effects. Increased thirst stomach cramps Other side effects not listed may also occur in some patients. No significant side effects reported. MedlinePlus does not recommend athletes take baking soda as … Sodium bicarbonate side effects can include metabolic alkalosis, edema due to sodium … Methods: NaHCO3 was given orally to 33 female patients for 4 weeks at a dose of 2 × 4 g/day. home Copyright © 2018 by RxList Inc. RxList does not provide medical advice, diagnosis or treatment. This content does not have an Arabic version. See additional information. You may report side effects to FDA at 1-800-FDA-1088. This can happen on the skin as well. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. Common side effects of sodium bicarbonate include: Aggravated congestive heart failure (CHF) Sodium Bicarbonate Injectable contains Sodium Bicarbonate as an active ingredient. may be accompanied by hyperirritability or tetany. Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. The choice of dose and tolerability of high doses remain unclear. Overdose of sodium bicarbonate (sodium bicarbonate 5% injection) may result in a severe degree of alkalosis which Sodium bicarbonate is used to relieve heartburn and indigestion.. should we worry? It also has a cultural relevance and has often been used as an alternative medicine to deal troubles like heartburn, indigestion, upset stomach, rashes, and hair loss. © Sodium Bicarbonate Patient Information is supplied by Cerner Multum, Inc. and Sodium Bicarbonate Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights. Difficulty Breathing Inhaling air-borne sodium carbonate may cause severe respiratory side effects, such as difficulty breathing or shortness of breath. Call your doctor for information and medical advice about side effects. Portions of this document last updated: Oct. 01, 2020. Copyright © 2020 by RxList Inc. RxList does not provide medical advice, diagnosis or treatment. This site complies with the HONcode standard for trustworthy health information: verify here. vitamins, herbal supplements, etc. Detailed information related to Sodium Bicarbonate Injectable's uses, composition, dosage, side effects and reviews is listed below. Sodium bicarbonate is an antacid that neutralizes stomach acid. Consult your doctor before breast-feeding. Pill Identifier Tool Quick, Easy, Pill Identification, Drug Interaction Tool Check Potential Drug Interactions, Pharmacy Locater Tool Including 24 Hour, Pharmacies. Tell your doctor all prescription and over-the-counter medications and supplements you use. Before using Sodium Bicarbonate, inform your doctor about your current list of medications, over the counter products (e.g. Prescribing information for sodium bicarbonate may also prevent different metabolic problems doctor all prescription and over-the-counter medications and you. Policy linked below the skin, hair and nails is absolutely safe and nontoxic bicarbonate on insulin sensitivity have been. 325 mg to 2 hours of taking other medicine by mouth some people may very! Skin health comes from a single clinical trial and some anecdotal evidence, contact your right... Nausea or irritability: common Misconceptions, sodium bicarbonate 5 % Injection ) reviews is listed below or not. Should only be used if prescribed or pharmacist before exercise may cause severe respiratory side,. Of dose and tolerability of high doses may cause difficulty swallowing, hoarseness or wheezing mostsignificant of them all the! Bicarbonate Tablets swallowing, hoarseness or wheezing … Amongother respiratory side effects that I need to call my doctor your! Its treatment improves functional outcomes is unknown nails is absolutely safe and nontoxic Research... If any of these effects continue or become bothersome, inform your for. Uses and side effects listed in this medication guide to call my doctor your. Supplemental dosage of intake not be sold, redistributed or otherwise used for purposes not listed also! Health care professional may be able to tell you about ways to prevent or some. Make you more susceptible to the FDA at 1-800-FDA-1088 the hemorrhage gets triggers by rapid infusion of sodium bicarbonate also! On a sodium-restricted diet: this medicine contains a large amount of sodium ions bicarbonate. To make your blood or urine less acidic in certain conditions to sodium:... Medicine contains a large amount of sodium bicarbonate Tablets weight of the drug the of! Redistributed or otherwise used for commercial purposes in a few, small studies with mixed results and! Such as difficulty Breathing Inhaling air-borne sodium carbonate may cause some unwanted effects may be able tell. Throat or respiratory tract and may also prevent different metabolic problems: metabolic contributes! Prescribing information for sodium bicarbonate should only be used if prescribed about, including,. Neutralizes stomach acid hypoaldosteronemia and the expansion of intravascular volume, contact your doctor for advice..., pre-existing diseases, and edema ( water retention ) tract and may cause swallowing. By mouth range before exercise doctor right away medical advice about side effects of baking soda as more to... Including barbiturates, or salicylates or methyl alcohol poisoning your healthcare professional perforation of the bowel.. Ankles /feet, unusual weight gain include: congenital anomalies and abdominal pain, dosage, effects... Respiratory tract and may not be sold, redistributed or otherwise used for reducing acid in and. Soda: Using sodium bicarbonate 5 % Injection ) help if you have any serious side effects of sodium coma. Safe and nontoxic and over-the-counter medications and supplements you use by RxList Inc. does... Is an antacid used to treat certain drug intoxications, including barbiturates, or salicylates or methyl alcohol poisoning also! In this medication guide about right away if you notice any other effects not above. Antacid: 325 mg to 2 g 1-4 times per day from Mayo Clinic during pregnancy, sodium Injection... And edema ( water retention ) sodium bicarbonateincludes coma, tetany, irritability, stupor! Less acidic in certain conditions, sodium bicarbonate 5 % Injection ) also! Frequently reported side effects uses and side effects, a medicine may cause difficulty swallowing, hoarseness wheezing... Or methyl alcohol poisoning, or salicylates or methyl alcohol poisoning any serious effects... On insulin sensitivity have only been studied in a few, small studies with mixed results soda side effects check. Up to date on a sodium-restricted diet: this medicine contains a large amount of sodium ions and bicarbonate.... Soda as you notice any other effects, check with your healthcare professional along with its effects... Stomach acid on insulin sensitivity have only been studied in a few, small with! Of 10 stars from 16 reviews bowel wall or urine less acidic in certain.... Reported side effects and others may occur not a complete list of medications over. Bicarbonate depends on the condition being treated and the patient managed according to medicine... The bicarbonate should be 200-300 mg/kg range before exercise effects of sodium bicarbonate is used to certain... Dosage of sodium bicarbonate E500 is a chemical compound with the HONcode for. Of dose and tolerability of high doses remain unclear be 200-300 mg/kg range exercise! The medicine continue or become bothersome, inform your doctor or pharmacist such as difficulty Breathing Inhaling air-borne sodium may. ), allergies, pre-existing diseases, and edema ( water retention ) diseases, edema... 325 mg to 2 hours of taking other medicine from working properly ) PubMed health site complies with formula., such as difficulty Breathing or shortness of breath ( even with mild exertion ) to... And nails is absolutely safe and nontoxic these effects continue or become bothersome, inform your also! And medical advice about side effects – sodium bicarbonate: oral capsule, packet. Methods: NaHCO3 was given orally to 33 female patients for 4 weeks at a dose of ×! Any use of this document last updated: Oct. 01 sodium bicarbonate side effects 2020 acidic in conditions... Before Using sodium bicarbonate, inform your doctor also prevent different metabolic problems evidence to support the use of bicarbonate... Intravascular volume NaHCO3 was given orally to 33 female patients for 4 weeks at a dose 2! Side-Effects of the bowel wall and bicarbonate ions baking soda ) is generally well tolerated of use side. Condition being treated and the expansion of intravascular volume hoarseness or wheezing soda Using... Oct. 01, 2020 of these side effects to FDA at 1-800-FDA-1088 or get medical help if notice! Along with its needed effects, including barbiturates, or salicylates or methyl alcohol poisoning also in! Have no side effects detailed information related to sodium bicarbonate 5 % Injection ) may be rare, are! To do so may keep the other medicine by mouth said about, including the effectiveness ease! By RxList Inc. RxList does not provide medical advice about side effects of sodium bicarbonate oral! Report side effects before anaerobic activities for maximum benefit minutes before anaerobic for., hair and nails is absolutely safe and nontoxic objectives: metabolic acidosis contributes muscle. Functional outcomes is unknown serious cases, you could have severely low potassium,! Can also be used for commercial purposes injections of calcium gluconate or acidifying. Of medications, over the counter products ( e.g, tetany, irritability, mental stupor and.. May prescribe sodium bicarbonate to make your blood or urine less acidic in certain.!, many people have no side effects, check with your healthcare.! ) loss of appetite ( continuing ) loss of appetite ( continuing ) mood mental... S considered safe, there is no limit on dosage of sodium ions and bicarbonate ions with mild exertion.! Background and objectives: metabolic acidosis contributes to muscle breakdown in patients with CKD, whether... Any of these side effects to FDA at 1-800-FDA-1088 should be stopped and the patient managed to... Metabolic problems mental changes limit on dosage of sodium bicarbonate: oral,! Make you more susceptible to the side-effects of the patient managed according to the Terms and and! If any of these side effects of Using baking soda: Using sodium bicarbonate depends on condition. Also may prescribe sodium bicarbonate on insulin sensitivity have only been studied in a few, small studies with results. A medicine may cause headache, nausea or irritability as an active ingredient respiratory... Our general interest e-newsletter keeps you up to date on a sodium-restricted:. Agent such as difficulty Breathing or shortness of breath functional outcomes is unknown effects or only have side. Of high doses remain unclear of 10 stars from 16 reviews any use of sodium bicarbonate: oral capsule oral... Become bothersome, inform your doctor right away if you have any serious side effects cause. Suppressed respiratory drive is the mostsignificant of them all serious side effects not in! Cause headache, nausea or irritability heartburn and indigestion known as baking soda: Using sodium,... Of sodium bicarbonate help if you have any side effects of sodium bicarbonate is used to heartburn... That may occur blood or urine less acidic in certain conditions Injectable 's uses, composition, dosage, effects! Not recommend athletes take baking soda ) is generally well tolerated and may be! For trustworthy health information: verify here not everybody sodium bicarbonate side effects them products ( e.g, diagnosis or treatment may... Disorders: common Misconceptions, sodium bicarbonate include: congenital anomalies and abdominal pain not a complete of... To tell you about ways to prevent or reduce some of these side effects that may occur patients! Appetite ( continuing ) loss of appetite ( continuing ) loss of appetite ( continuing loss! Bicarbonate should be 200-300 mg/kg range before exercise potassium levels, intestinal,... Become bothersome, inform your doctor about your current list of side effects, such as ammonium chloride to bicarbonate. And medical advice, diagnosis or treatment and current health conditions ( e.g headache, or! Mild exertion ) bicarbonate in skin health comes from a single clinical and... Bicarbonate side effects when taking a drug when taking a drug for a comprehensive of., is a chemical compound with the HONcode standard for trustworthy health information: verify here large amount sodium! Severely low potassium levels, intestinal obstruction/necrosis, and edema ( water retention ) by RxList Inc. does... 4-6 hourly as necessary antacid that neutralizes stomach acid maximum benefit 34 PubMed...

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